ABOUT
Mitsubishi Chemical has a long track record of adoption of urethane resins for medical use.
We acquired AdvanSource Biomaterials Corporation in North America in 2020.
We supply urethane-based resins (various compounds and coatings) used in implants and catheter products.
Flexible customization is also possible to meet a wide range of mechanical properties and processing method needs.
FEAUTURE
Mitsubishi Chemical's urethane resins have high biocompatibility, allowing us to offer a wide range of materials tailored to various applications and required properties, such as implantation in the body and high sliding properties.
Furthermore, our products are manufactured and developed under ISO 13485 certification and comply with various biological safety assessments, including USP Class VI.
Please verify suitability for your intended use with the final product.
■ChronoFlex™ (Carbonate-based)
It has high chemical resistance and mechanical properties, and excellent long-term durability.
Main intended uses: Intra-implantable devices such as CV ports, implantable devices
Isocyanates: Aliphatic or aromatic
Hardness range: 75A to 75D
■HydroThane™ (Hydrophilic)
It offers excellent sliding properties and flexibility within the body (in water).
Main intended uses: Catheters and devices for implantation in the body for less than 30 days.
Isocyanates: Aliphatic or aromatic
Hardness range: 80A to 93A
■Polyblend 1100™
An ultra-flexible elastomer that cannot be achieved with thermoplastic polyurethane.
Main intended uses: Balloon catheters and devices for implantation in the body for less than 30 days.
Isocyanates: Aromatic compounds
Hardness range: 12A to 80A
■ChronoThane™ (Ether-based)
It exhibits excellent mechanical properties, including tensile elongation.
Main intended uses: Catheters and devices for implantation in the body for less than 30 days.
Isocyanates: Aliphatic or aromatic
Hardness range: 75A to 75D
■HydroMed™ (For coating purposes only)
This superhydrophilic urethane coating provides lubrication through its high water absorption properties.
Main intended use: Indwelling devices for less than 30 days
Isocyanates: Aliphatic compounds
Chrono Flex™ C | Chrono Flex™ AL | ChronoThan™P | ChronoThan™T | HydroThane™ AR | HydroThane™ AL | HydroMed™ AL | PolyBlend 1100™ | |
Isocyanate type | aromatic | aliphatic | aromatic | aliphatic | aromatic | aliphatic | aliphatic | aromatic |
Polyol type | Polycarbonate | Polycarbonate | ether | ether | ether | ether | ether | ether |
Hardness range | 75A-75D | 75A-75D | 75A-75D | 75A-75D | 80A-93D | 80A-93D | - | - |
contrast agent | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | - |
Biocompatibility | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
Biocompatibility | ✓ | ✓ | - | - | - | - | - | - |
item | Test method | Chrono Flex™C | Chrono Students™ AL | ChronoThane™ P | ChronoThane™T | HydroThane™ AR | HydroThane™ AL | HydroMed™ AL | PolyBlend 1100™ |
Cytotoxicity test: MEM Elution method | ISO10993-5 | Compatibility | Compatibility | Compatibility | Compatibility | Compatibility | Compatibility | Compatibility | Compatibility |
Systemic toxicity test | USP Class VI | Compatibility | Compatibility | Compatibility | Compatibility | Compatibility | Compatibility | ‐ | ‐ |
Inflammation and skin sensitization | USP Class VI | Compatibility | Compatibility | Compatibility | Compatibility | Compatibility | Compatibility | ‐ | ‐ |
Burial experiment | USP Class VI | Compatibility | Compatibility | Compatibility | Compatibility | Compatibility | Compatibility | ‐ | ‐ |
Phthalate (DEHP) free | ー | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
Animal-derived ingredient (BSE/TSE) free | ー | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
CASE


CONTACT
Polymer Compounds Business Group Products
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The above information is based on the latest available information as of the date of creation and may be revised in the future based on new information.
Furthermore, this information is provided as general technical information and reference material, and we do not guarantee the accuracy or completeness of the content.
Product performance and characteristics may vary depending on usage conditions, processing conditions, etc. The final decision regarding applicability and design is the customer's responsibility.
We will check the regulations of each country regarding the export of chemical products and then respond whether or not we can provide them. Please be sure to include information such as the exporting country.
Depending on the product, we may suggest a different grade or may not be able to provide the product at all.
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